Реакция #2069924

Уравнение реакции

Acetic anhydride

4-isopropylaniline

→

N-Acetyl-4-isopropylaniline

Растворители

chloroform

Условия реакции

Обработка

1. 1
   ТемператураIn the course of this, intense heating of the reaction mixture
2. 2
   workup.ADDITIONOn completion of the dropwise addition
3. 3
   КонцентрированиеThe reaction mixture is concentrated to dryness
4. 4
   Другоеthe resulting, reddish-white solid is recrystallized from hexane

Методика

Acetic anhydride (26.0 g, 254 mmol) is slowly added dropwise to a solution of 4-isopropylaniline (17.2 g, 127 mmol) in 80 ml of chloroform. In the course of this, intense heating of the reaction mixture occurs. On completion of the dropwise addition, the mixture is stirred at room temperature for another 2 h. The reaction mixture is concentrated to dryness and the resulting, reddish-white solid is recrystallized from hexane.

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