Реакция #2057

ord-d450d9a3b4314144865c4274817143d7

Уравнение реакции

CCCCCCCCCCCCCCCCCCN(C)CCO
N-(2-hydroxyethyl)-N-methyloctadecylamine
CCCCCCCCCCCCCCCCCC(=O)O
octadecanoic acid
→
CCCCCCCCCCCCCCCCCCN(C)CCOC(=O)CCCCCCCCCCCCCCCCC
N-(2-octadecanoyloxyethyl)-N-methyloctadecylamine
Выход 96.5%

Реактанты

CCCCCCCCCCCCCCCCCCN(C)CCO
N-(2-hydroxyethyl)-N-methyloctadecylamine
CCCCCCCCCCCCCCCCCC(=O)O
octadecanoic acid

Реагенты

Нет

Условия реакции

Температура
180°CELSIUS
Подробные условия
See reaction.notes.procedure_details.

Обработка

  1. 1
    ДругоеA four-neck flask provided with a stirrer
  2. 2
    Температураmaintained at this temperature for 12 hours
  3. 3
    workup.DISTILLATIONwhile distilling off the water
  4. 4
    Другоеthus formed

Методика

A four-neck flask provided with a stirrer, a thermometer and a dehydrating tube was charged with 200 g of the N-(2-hydroxyethyl)-N-methyloctadecylamine and 174 g of octadecanoic acid. The mixture was heated to 180° C. and maintained at this temperature for 12 hours while distilling off the water thus formed. Thus 350 g of N-(2-octadecanoyloxyethyl)-N-methyloctadecylamine was obtained. Based on the NMR and IR spectra, it was confirmed that this product had the following structure. This compound will be referred to as the enhancer 25 hereinafter. ##STR31##

Источник

DOI: 10.6084/m9.figshare.5104873.v1Патент: US05728649uspto-grants-1998_03