Реакция #2028881

Уравнение реакции

alcohol

4-[3-hydroxymethyl-5-phenyl-1H-pyrazol-1-yl]benzene Sulfonamide

→

aldehyde

4-[3-formyl-5-phenyl-1H-pyrazol-1-yl]benzenesulfonamide

Растворители

ethyl acetate

Условия реакции

Обработка

1. 1
   ФильтрацияThe mixture was filtered through Celite
2. 2
   Концентрированиеthe solution was concentrated

Методика

To a solution of the alcohol prepared in Example 131, Step 3 (1.1 g, 3.3 mmol) in ethyl acetate (20 mL) was added MnO2 (5 g, 60 mmol) and the mixture stirred at room temperature overnight. The mixture was filtered through Celite and the solution was concentrated to provide the crude aldehyde.

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