Реакция #2009328
ord-25b2c3e642614ff2aad6730fb1e15bc9
Уравнение реакции
{8-chloro-2-difluoromethoxy-4-methyl-3-[4-(4,4,5,5-tetramethyl[1,3,2]dioxaborolan-2-yl)benzyl]quinolin-5-yloxy}acetic acid tert-butyl ester
3-chloro-1H-pyrazole
→
title compound
{8-chloro-3-[4-(3-chloropyrazol-1-yl)benzyl]-2-difluoromethoxy-4-methylquinolin-5-yloxy}acetic acid tert-butyl ester
Реактанты
Реагенты
Нет
Условия реакции
Подробные условия
See reaction.notes.procedure_details.
Методика
The title compound was prepared by the method of Preparation 18a using {8-chloro-2-difluoromethoxy-4-methyl-3-[4-(4,4,5,5-tetramethyl[1,3,2]dioxaborolan-2-yl)benzyl]quinolin-5-yloxy}acetic acid tert-butyl ester and 3-chloro-1H-pyrazole.