Реакция #1994252

Уравнение реакции

water

carbazole

sodium hydroxide

allylbromide

→

N-Allylcarbazole

Растворители

dimethylsulfoxide

Условия реакции

Обработка

1. 1
   Экстракцияextracted with ethyl acetate
2. 2
   ПромывкаThe ethyl acetate layer was washed with water
3. 3
   Концентрированиеconcentrated
4. 4
   ДругоеThe crude product was purified

Методика

A mixture of 10.85 g (65.0 mmol) of carbazole, 2.60 g (65.0 mmol) of sodium hydroxide and 6.1 mL (72.0 mmol) of allylbromide in 100 mL dimethylsulfoxide was heated to 60° C. for 5 hours. The reaction mixture was poured into water and extracted with ethyl acetate. The ethyl acetate layer was washed with water and then concentrated. The crude product was purified using column chromatography (silica, 1:4 dichloromethane:hexane). Yield: 9.85 g (73%).

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