Реакция #1960497

Уравнение реакции

5,6-difluoro-3-(4-propylcyclohexyl)-1,2-dihydronaphthalene

→

7,8-difluoro-2-(4-propylcyclohexyl)-1,2,3,4-tetrahydronaphthalene

Растворители

THF

Условия реакции

Обработка

1. 1
   Другоеare hydrogenated at RT
2. 2
   ФильтрацияThe reaction solution is filtered
3. 3
   Другоеevaporated to dryness
4. 4
   ДругоеThe residue is used for the following reaction without further purification

Методика

76.0 g (0.26 mol) of 5,6-difluoro-3-(4-propylcyclohexyl)-1,2-dihydronaphthalene are hydrogenated at RT and atmospheric pressure for 19 h in 500 ml of THF in the presence of Pd/C (5% of Pd). The reaction solution is filtered and evaporated to dryness. The residue is used for the following reaction without further purification.

Источник