Реакция #1909799

Уравнение реакции

4-Phenylsulfanyl-[1,3]dioxolan-2-one

OXONE

water

→

4-benzenesulfonyl-[1,3]dioxolan-2-one

Растворители

methanol

methanol

Условия реакции

Обработка

1. 1
   ДругоеThe obtained reaction mixture
2. 2
   workup.STIRRINGwas agitated at room temperature for 12 hours
3. 3
   Другоеwas removed
4. 4
   workup.DISTILLATIONdecompression distillation
5. 5
   Экстракцияthe resulting product was extracted
6. 6
   ЭкстракцияThe extracted organic solvent layer was again extracted
7. 7
   Другоеwas removed
8. 8
   Другоеorganic solvent was removed
9. 9
   workup.DISTILLATIONdecompression distillation
10. 10
    ДругоеUsing silica gel chromatography, separation and purification

Методика

4-Phenylsulfanyl-[1,3]dioxolan-2-one) was dissolved in methanol, and OXONE® was added. The resulting mixture was agitated at room temperature for 5 minutes and water was added. The obtained reaction mixture was agitated at room temperature for 12 hours. From the agitated reaction mixture, methanol was removed using decompression distillation and the resulting product was extracted using methylene chloride. The extracted organic solvent layer was again extracted using water, moisture was removed using magnesium sulfate, and then organic solvent was removed using decompression distillation. Using silica gel chromatography, separation and purification were performed to obtain a pure target product, 4-benzenesulfonyl-[1,3]dioxolan-2-one.

Источник