Реакция #1876820

Уравнение реакции

1,3,5-trihydroxyadamantane

trimethylamine

trimethylsilyl chloride

→

1,3-dihydroxy-5-trimethylsiloxyadamantane

Растворители

methylene chloride

Условия реакции

Обработка

1. 1
   ДругоеReaction
2. 2
   Другоеwas carried out at room temperature
3. 3
   ДругоеThe reaction product was partitioned by high performance liquid chromatography

Методика

This 1,3,5-trihydroxyadamantane was dissolved in methylene chloride. To this solution were added a small amount of trimethylamine, and then an equimolar amount of trimethylsilyl chloride. Reaction was carried out at room temperature. The reaction product was partitioned by high performance liquid chromatography to obtain 1,3-dihydroxy-5-trimethylsiloxyadamantane.

Источник