Реакция #1811

Уравнение реакции

ammonia

isothiocyanatoacetaldehyde dimethyl acetal

→

title compound

N-(2,2-Dimethoxyethyl)thiourea

Растворители

Methanol

Условия реакции

Обработка

1. 1
   КонцентрированиеThe mixture was concentrated
2. 2
   Другоеthe residue was chromatographed (silica gel, 5% methanol/dichloromethane)

Методика

Methanol (200 mL) was saturated with ammonia and stirred with isothiocyanatoacetaldehyde dimethyl acetal (5.0 g) for 2 h. The mixture was concentrated and the residue was chromatographed (silica gel, 5% methanol/dichloromethane) to give the title compound.

Источник