Реакция #1795427

Уравнение реакции

5-{[3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl]methylene}-4-thiazolidinone

bromoacetonitrile

sodium hydride

→

desired title product

Выход 40.7%

5-{[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methylene}-4-oxo-3-thiazolidineacetonitrile

Выход 40.7%

Растворители

tetrahydrofuran

Условия реакции

Методика

7.03 g of 5-{[3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl]methylene}-4-thiazolidinone and 2.64 g of bromoacetonitrile were reacted in the presence of 0.97 g of 60% sodium hydride in mineral oil and 330 ml of tetrahydrofuran. Work-up of the reaction mixture provided 3.21 g of the desired title product, m.p. 168°-188° C.

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