Реакция #1755446

Уравнение реакции

glyoxylic acid

L-cystine

borate

→

N,N,N′,N′-tetrakis(carboxymethyl)-L-cystine

Условия реакции

Обработка

1. 1
   ДругоеThe alternative route, relying on in-solution phase synthesis of an intermediate product
2. 2
   Другоеpurified with ion exchange chromatography

Методика

The alternative route, relying on in-solution phase synthesis of an intermediate product starts with addition of a large excess (40 times) of glyoxylic acid to L-cystine in an alkaline borate buffer. The intermediate product, following pH manipulation and conductivity adjustment of the reaction mixture, purified with ion exchange chromatography to give N,N,N′,N′-tetrakis(carboxymethyl)-L-cystine.

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