Реакция #1747852

Уравнение реакции

4-carboxyphenylthiourea

DIC

→

Phenylthiourea

Растворители

DMF

Условия реакции

Обработка

1. 1
   ДругоеAminopropylsilylated glass surfaces purified with compressed air (2.5×7.5 cm; Sigma, Silane-Prep™, S4651)
2. 2
   Другоеthus obtained
3. 3
   workup.ADDITIONThe glass surfaces thus treated
4. 4
   Промывкаwere then washed five times
5. 5
   Другоеfor 3 minutes
6. 6
   Другоеat room temperature
7. 7
   ПромывкаAfter washing three times for three minutes each using respectively 30 mL of DCM at room temperature
8. 8
   Другоеthe glass surfaces were dried
9. 9
   Другоеstored at 4° C. until further use

Методика

4-carboxyphenylthiourea (Lancaster, 13047) was dissolved to 0.2M in DMF. The resultant mixture was activated by adding a half equivalent of DIC for 15 min at room temperature. Aminopropylsilylated glass surfaces purified with compressed air (2.5×7.5 cm; Sigma, Silane-Prep™, S4651) were coated with the activated solution thus obtained and incubated for three hours at room temperature. The glass surfaces thus treated were then washed five times using respectively 30 mL of DMF for 3 minutes each at room temperature. After washing three times for three minutes each using respectively 30 mL of DCM at room temperature, the glass surfaces were dried and stored at 4° C. until further use.

Источник