Реакция #172508

Уравнение реакции

4-(dibutylamino)-2-methoxybenzaldehyde

1,3-bis(dicyanomethylidene)indan

water

→

black crystal

Выход 86.5%

2-[2-(4-dibutylamino-2-methoxybenzylidene)-3-dicyanomethyleneindan-1-ylidene]malonnitrile

Выход 86.5%

Растворители

acetic acid

Условия реакции

Обработка

1. 1
   Другоеthe precipitate was separated by filtration
2. 2
   Промывкаwashed with water
3. 3
   Другоеdried
4. 4
   ДругоеThe crystal was purified by silica gel column chromatography
5. 5
   Промывкаwashed with methanol

Методика

In 10 ml of anhydrous acetic acid were dissolved 0.8 g (3.04 mmol) of 4-(dibutylamino)-2-methoxybenzaldehyde and 0.73 g (3.01 mmol) of 1,3-bis(dicyanomethylidene)indan. The mixture was stirred with heating at 80° C. for 2 hours. The reaction mixture was poured into 200 ml of water and the precipitate was separated by filtration, washed with water, and dried. The crystal was purified by silica gel column chromatography and washed with methanol to give 1.27 g of a black crystal having a mp of 195-198° C. (yield: 86.4%).

Источник