Реакция #1605811

Уравнение реакции

2-Phenylaniline

acetic anhydride

→

2-phenyl-N-acetylaniline

Выход 99.5%

Растворители

acetic acid

Условия реакции

Обработка

1. 1
   КонцентрированиеThe solution was concentrated under reduced pressure
2. 2
   workup.ADDITIONto the residue was added water (15 mL)
3. 3
   workup.STIRRINGthe mixture was stirred at room temperature for 3 hours
4. 4
   ФильтрацияThe precipitate was collected by filtration
5. 5
   Промывкаwashed with purified water
6. 6
   Другоеdried under reduced pressure

Методика

2-Phenylaniline (5 g, 29.55 mmol) was dissolved in acetic acid (30 mL), acetic anhydride (3.62 g, 35.45 mmol) was added thereto under ice bath, and the mixture was stirred under ice bath for 2 hours. The solution was concentrated under reduced pressure. to the residue was added water (15 mL), and the mixture was stirred at room temperature for 3 hours. The precipitate was collected by filtration, washed with purified water, and dried under reduced pressure to obtain 2-phenyl-N-acetylaniline (6.21 g).

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