Реакция #1605802

Уравнение реакции

tert-butyl 3-[3-({[(1-methylpiperidin-4-yl)oxy]carbonyl}amino)-4-phenylphenyl]propionate

hydrochloric acid

→

3-[3-({[(1-methylpiperidin-4-yl)oxy]carbonyl}amino)-4-phenylphenyl]propionate hydrochloride

Растворители

dioxane

Условия реакции

Обработка

1. 1
   КонцентрированиеThe reaction solution was concentrated under reduced pressure

Методика

To tert-butyl 3-[3-({[(1-methylpiperidin-4-yl)oxy]carbonyl}amino)-4-phenylphenyl]propionate (5.08 g, 11.6 mmol) was added a 4M solution of hydrochloric acid in dioxane (70 mL) and the mixture was stirred at 70° C. for 2 hours. The reaction solution was concentrated under reduced pressure to obtain 3-[3-({[(1-methylpiperidin-4-yl)oxy]carbonyl}amino)-4-phenylphenyl]propionate hydrochloride (5.49 g).

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