Реакция #160248

ord-bed8935557e24b1eb9e19d1fe29ca3f4

Уравнение реакции

COC(=O)c1ccc(S(=O)(=O)Cl)cc1
methyl 4-(chlorosulfonyl)benzoate
Cn1ccc2cc(CN)ccc21
(1-methyl-1H-indol-5-yl)methanamine
→
COC(=O)c1ccc(S(=O)(=O)NCc2ccc3c(ccn3C)c2)cc1
titled compound
COC(=O)c1ccc(S(=O)(=O)NCc2ccc3c(ccn3C)c2)cc1
Methyl 4-(N-((1-methyl-1H-indol-5-yl)methyl)sulfamoyl)benzoate

Реактанты

COC(=O)c1ccc(S(=O)(=O)Cl)cc1
methyl 4-(chlorosulfonyl)benzoate
Cn1ccc2cc(CN)ccc21
(1-methyl-1H-indol-5-yl)methanamine

Реагенты

Нет

Условия реакции

Подробные условия
See reaction.notes.procedure_details.

Методика

The titled compound was prepared according to the procedure described in step-1 of Example 1 from methyl 4-(chlorosulfonyl)benzoate and (1-methyl-1H-indol-5-yl)methanamine.

Источник

DOI: 10.6084/m9.figshare.5104873.v1Патент: US08829026B2uspto-grants-2014_09