Реакция #1596523

Уравнение реакции

diphenyliodonium chloride

triethylammonium 2-pivaloyloxy-1,1-difluoroethanesulfonate

water

→

target compound

Выход 96.6%

Diphenyliodonium 2-Pivaloyloxy-1,1-difluoroethanesulfonate

Выход 96.6%

Растворители

chloroform

Условия реакции

Обработка

1. 1
   Другоеreacted at room temperature for 3 hours
2. 2
   ДругоеThe thus-obtained reaction solution
3. 3
   Другоеwas separated into an organic layer
4. 4
   ПромывкаThe organic layer was washed five times with 15 mL of water
5. 5
   Концентрированиеsubjected to concentration under reduced pressure

Методика

In 10 mL of chloroform, 5 g of a solid of triethylammonium 2-pivaloyloxy-1,1-difluoroethanesulfonate (equivalent to 14.4 mmol) was dissolved by stirring. The resulting solution was admixed with 15 mL of water and 4.78 g (15.1 mmol) of diphenyliodonium chloride, and then, reacted at room temperature for 3 hours. The thus-obtained reaction solution was separated into an organic layer and an aqueous layer. The organic layer was washed five times with 15 mL of water and subjected to concentration under reduced pressure. With this, 7.32 g of the target compound was obtained as a white solid (purity: 90%, yield: 90%).

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