Реакция #1581416

Уравнение реакции

1-(6-iodohexyl)-2,3-bis(phenylmethoxy)benzene

2,5-dihydroxybenzoic acid methyl ester

potassium carbonate

→

2-hydroxy-5-[6-[2,3-bis(phenylmethoxy)phenyl]hexyloxy]benzoic acid methyl ester

Выход 39.0%

Растворители

acetone

Условия реакции

Обработка

1. 1
   Температураat reflux for 17 hours

Методика

A mixture of 1.00 g of 1-(6-iodohexyl)-2,3-bis(phenylmethoxy)benzene, 0.34 g of 2,5-dihydroxybenzoic acid methyl ester and 1.0 g of potassium carbonate in 30 mL of acetone was stirred at reflux for 17 hours. Workup as in Example 16 and chromatography on 60 g of silica gel using 1% ethyl acetate-toluene gave 0.42 g (39% yield) of 2-hydroxy-5-[6-[2,3-bis(phenylmethoxy)phenyl]hexyloxy]benzoic acid methyl ester as an oil.

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