Реакция #156693

Уравнение реакции

1-[(R)-1-(4-Amino-2-fluoro-phenyl)-pyrrolidin-3-yl]-4-methyl-piperidin-4-ol

6-[(S)-1-(Tetrahydro-furan-2-yl)methoxy]-isochroman-1-one

→

2-{3-Fluoro-4-[(R)-3-(4-hydroxy-4-methyl-piperidin-1-yl)-pyrrolidin-1-yl]-phenyl}-6-[(S)-1-(tetrahydro-furan-2-yl)methoxy]-3,4-dihydro-2H-isoquinolin-1-one

Условия реакции

Обработка

1. 1
   ДругоеThe product with the molecular weight of 523.65 (C30H38FN3O4) was obtained in this way

Методика

1-[(R)-1-(4-Amino-2-fluoro-phenyl)-pyrrolidin-3-yl]-4-methyl-piperidin-4-ol was reacted with 6-[(S)-1-(Tetrahydro-furan-2-yl)methoxy]-isochroman-1-one by method AC. The product with the molecular weight of 523.65 (C30H38FN3O4) was obtained in this way; MS (ESI): 524 (M+H+).

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