Реакция #156626

Уравнение реакции

6-cyclopropylmethoxy-2-[4-(2,7-diaza-spiro[4.4]non-2-yl)-3-fluorophenyl]-2H-isoquinolin-1-one

1-bromo-2-fluoro-ethane

→

6-Cyclopropylmethoxy-2-{3-fluoro-4-[7-(2-fluoroethyl)-2,7-diaza-spiro[4.4]non-2-yl]-phenyl}-2H-isoquinolin-1-one

Условия реакции

Обработка

1. 1
   ДругоеIn this way the product was obtained with molecular weight 479.57 (C28H31F2N3O2)

Методика

According to Method X, 6-cyclopropylmethoxy-2-[4-(2,7-diaza-spiro[4.4]non-2-yl)-3-fluorophenyl]-2H-isoquinolin-1-one was reacted with 1-bromo-2-fluoro-ethane. In this way the product was obtained with molecular weight 479.57 (C28H31F2N3O2); MS (ESI): 480 (M+H+).

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