Реакция #1519123

Уравнение реакции

(S)-N-(trifluoroacetyl)prolyl chloride

1-amino-propan-2-one

→

1-trifluoroacetyl-pyrrolidine-2-carboxylic acid (2-oxo-propyl)-amide

Растворители

DCM

pyridine

Условия реакции

Методика

A solution of (S)-N-(trifluoroacetyl)prolyl chloride (Aldrich) 1 equiv. in DCM is treated with 1-amino-propan-2-one (1.5 equiv.) in pyridine at rt for 5 hours. After usual work up, it provides 1-trifluoroacetyl-pyrrolidine-2-carboxylic acid (2-oxo-propyl)-amide.

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