Реакция #1458423

ord-57511fb35fba4e78bf65bcc75ae4e06a

Уравнение реакции

CCCCCCCCCCC[C@H](CC(=O)NC(CCOP(=O)(Oc1ccccc1)Oc1ccccc1)C(=O)O)OCc1ccccc1
4-(diphenyloxyphosphoryloxy)-2-[(R)-3-benzyloxytetradecanoylamino]-butanoic acid
CCCCCCCCCCCC(=O)O[C@H](CCCCCCCCCCC)CC(=O)O
(R)-3-dodecanoyloxytetradecanoic acid
CCCCCCCCCCC[C@H](CC(=O)O)OCc1ccccc1
(R)-3-benzyloxytetradecanoic acid
→
CCCCCCCCCCCC(=O)O[C@H](CCCCCCCCCCC)CC(=O)NC(CCOP(=O)(Oc1ccccc1)Oc1ccccc1)C(=O)O
4-(diphenyloxyphosphoryloxy)-2-[(R)-3-dodecanoyloxytetradecanoylamino]-butanoic acid

Реактанты

CCCCCCCCCCC[C@H](CC(=O)NC(CCOP(=O)(Oc1ccccc1)Oc1ccccc1)C(=O)O)OCc1ccccc1
4-(diphenyloxyphosphoryloxy)-2-[(R)-3-benzyloxytetradecanoylamino]-butanoic acid
CCCCCCCCCCCC(=O)O[C@H](CCCCCCCCCCC)CC(=O)O
(R)-3-dodecanoyloxytetradecanoic acid
CCCCCCCCCCC[C@H](CC(=O)O)OCc1ccccc1
(R)-3-benzyloxytetradecanoic acid

Реагенты

Нет

Условия реакции

Подробные условия
See reaction.notes.procedure_details.

Обработка

  1. 1
    Другоеthe same reaction scheme

Методика

The 4-(diphenyloxyphosphoryloxy)-2-[(R)-3-benzyloxytetradecanoylamino]-butanoic acid can be prepared using the same reaction scheme by replacing in step 5 of example I, (R)-3-dodecanoyloxytetradecanoic acid by (R)-3-benzyloxytetradecanoic acid.

Источник

DOI: 10.6084/m9.figshare.5104873.v1Патент: US07157092B1uspto-grants-2007_01