Реакция #1380

Уравнение реакции

2-methyl-3-nitrobenzoic acid

methanol

thionyl chloride

→

methyl 2-methyl-3-nitrobenzoate

Условия реакции

Обработка

1. 1
   ТемператураAfter reflux for 2 hours
2. 2
   Экстракцияextracted with dichloromethane
3. 3
   КонцентрированиеThe solvent is concentrated

Методика

To 2-methyl-3-nitrobenzoic acid (10.0 g) is added methanol (100 ml) and thereto thionyl chloride (8 ml) is added dropwise at room temperature. After reflux for 2 hours, the reaction mixture is poured into ice-water and extracted with dichloromethane. The solvent is concentrated to give methyl 2-methyl-3-nitrobenzoate (10.8 g).

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