Реакция #1375813

Уравнение реакции

methyl 4-tri-n-butylstannylbenzoate

KOH

acetic acid

water

→

title compound

Выход 90.3%

4-Tri-n-butylstannylbenzoic acid

Выход 90.3%

Растворители

ethanol

Условия реакции

Обработка

1. 1
   ТемператураThe resulting solution was refluxed for 2 hours
2. 2
   ТемператураThe solution was cooled
3. 3
   ЭкстракцияThe solution was then extracted with diethyl ether (80 ml)
4. 4
   ПромывкаThe ether phase was washed with water (30 ml)
5. 5
   Сушкаdried over MgSO4 (5 g)
6. 6
   Фильтрацияfiltered
7. 7
   Другоеevaporated under reduced pressure

Методика

To a solution of methyl 4-tri-n-butylstannylbenzoate (3.0 g, 7 mmol) in absolute ethanol (60 ml) was added 0.25 g KOH (9 mmol). The resulting solution was refluxed for 2 hours. The solution was cooled and poured into an ice-cold solution of acetic acid (0.64 g, 10.6 mmol) and water (100 ml). The solution was then extracted with diethyl ether (80 ml). The ether phase was washed with water (30 ml), dried over MgSO4 (5 g), filtered and evaporated under reduced pressure to afford 2.6 g (88%) of the title compound. This material was used without further purification.

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