Реакция #1372

Уравнение реакции

ethyl 2-methyl-3,4,6-trifluorobenzoylacetate

acetic anhydride

triethoxymethane

→

ethyl 2-(2-methyl-3,4,6-trifluorobenzoyl)-3-ethoxyacrylate

Выход 90.0%

Условия реакции

Обработка

1. 1
   Температураthe mixture is refluxed for 1 hour
2. 2
   КонцентрированиеAfter concentrating

Методика

To ethyl 2-methyl-3,4,6-trifluorobenzoylacetate (3.2 g) are added acetic anhydride (3.0 g) and triethoxymethane (2.7 g) and the mixture is refluxed for 1 hour. After concentrating, ethyl 2-(2-methyl-3,4,6-trifluorobenzoyl)-3-ethoxyacrylate (3.5 g) is obtained.

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