Реакция #1244247

Уравнение реакции

propanoyl chloride

4-Phenylazophenol

triethylamine

→

product

Выход 72.0%

Propionic acid 4-phenylazo-phenyl ester

Выход 72.0%

Растворители

ether

ether

Условия реакции

Обработка

1. 1
   Другоеreaction
2. 2
   ПромывкаThe reaction mixture was washed with water
3. 3
   workup.ADDITIONdilute acid and brine
4. 4
   Сушкаdried with magnesium sulfate
5. 5
   ДругоеThe solvent was evaporated

Методика

4-Phenylazophenol (0.25 g, 1.26 mmoles) was dissolved in ether (5-10 mL) and triethylamine (0.26 mL) was added. Then propanoyl chloride (0.14 g 1.5 mmoles) in ether (1 mL) was added dropwise at room temperature. The mixture was stirred and reaction was rapidly completed. The reaction mixture was washed with water, dilute acid and brine and dried with magnesium sulfate. The solvent was evaporated to give 0.23 g (72%) of product. 1H NMR (CDCl3) δ=1.16 (3H, t, J=7.7), 2.40 (2H, q J=7.7), 7.25 (2H, m), 7.40-7.58 (3H, m), 7.88-8.0 (4H, m) ppm.

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