Реакция #12079

Уравнение реакции

sodium chlorodifluoroacetate

chlorotriethoxysilane

→

chlorodifluoroacetic acid, triethoxysilyl ester

Растворители

Et2O

Et2O

Условия реакции

Обработка

1. 1
   Температураto warm up to room temperature
2. 2
   ДругоеNaCl is removed by filtration and solution
3. 3
   Другоеevaporated to dryness

Методика

15.246 g (0.10 mol) sodium chlorodifluoroacetate, is dissolved to 100 mL Et2O and cooled to −70° C. 19.7 mL (0.10 mol, 19.872 g) chlorotriethoxysilane in Et2O (50 mL) was added dropwise to reaction solution. The solution was stirred for over night allowing it to warm up to room temperature. NaCl is removed by filtration and solution evaporated to dryness to result clear colourless liquid, chlorodifluoroacetic acid, triethoxysilyl ester.

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