Реакция #11965

Уравнение реакции

compound

(S)-2-(4-(N-Boc-aminomethyl)benzoylamino)-4-(N-Boc-amino)butyric acid

hydrochloric acid dioxane

→

title compound

Выход 189.4%

(S)-2-(4-aminomethylbenzoylamino)-4-aminobutyric acid

Выход 189.4%

Растворители

methanol

Условия реакции

Обработка

1. 1
   ДругоеAfter the reaction
2. 2
   Другоеthe solvent was removed by distillation
3. 3
   Другоеthe residue was dried

Методика

The compound obtained in Example 60-2 (49.7 mg) was dissolved in methanol (0.5 ml) and 4 mol/l hydrochloric acid/dioxane solution (0.5 ml) was added. The mixture was stirred for 1.5 hours at room temperature. After the reaction, the solvent was removed by distillation and the residue was dried using a vacuum pump to obtain the title compound (52.4 mg) as a white solid.

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