Реакция #1194905

Уравнение реакции

Trimethylsilyl chloride

m-bromocinnamic acid

→

Methyl m-bromocinnamate

Растворители

methanol

Условия реакции

Обработка

1. 1
   Другоеthe mixture was evaporated
2. 2
   Другоеto give product as a white solid, M+ 242

Методика

Trimethylsilyl chloride (5.6 ml) was added dropwise to a stirred solution of m-bromocinnamic acid (5.0 g, 22 mmol) in methanol (110 ml). After 4 h, the mixture was evaporated to give product as a white solid, M+ 242; 360 MHz 1H n.m.r (CDCl3) 7.67 (1H, s), 7.60 (1H, d, J 16 Hz), 7.50 (1H, d, J 7.9 Hz), 7.43 (1H, d, J 7.9 Hz), 7.26 (1H, d, J 15.6 Hz), 6.43 (1H, d, J 16.1 Hz), 3.81 (3H, s).

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