Реакция #1178397

Уравнение реакции

p-methoxybenzophenone

→

1,2-Bis(4-methoxyphenyl)-1,2-diphenylethene

Выход 91.0%

Растворители

THF

Условия реакции

Обработка

1. 1
   Температураwas refluxed for 20 h
2. 2
   Фильтрацияfiltered
3. 3
   ДругоеThe filtrates were evaporated
4. 4
   Другоеthe crude product was purified by a silica gel column

Методика

A suspension of p-methoxybenzophenone (1.06 g, 5.0 mmol), 1.34 equiv of TiCl3/AlCl3 (5.81 g, 6.7 mmol), and 25 equiv of Zn dust (8.01 g, 122.0 mmol) in 100 ml of dry THF was refluxed for 20 h. The reaction mixture was cooled to room temperature and filtered. The filtrates were evaporated and the crude product was purified by a silica gel column using hexane as eluent. 1,2-Bis(4-methoxyphenyl)-1,2-diphenylethene (TPE-OMe) was isolated in 91% yield.

Источник