Реакция #1178395

Уравнение реакции

4,4′-dihydroxybenzophenone

→

1,1,2,2-tetrakis(4-hydroxyphenyl)ethylene

Выход 83.0%

Растворители

THF

Условия реакции

Обработка

1. 1
   Температураwas refluxed for 20 h
2. 2
   Фильтрацияfiltered
3. 3
   ДругоеThe filtrates were evaporated
4. 4
   Другоеthe crude product was purified by a silica gel column
5. 5
   ДругоеDHTPE was obtained as slight yellow powder of 83% yield

Методика

A suspension of 4,4′-dihydroxybenzophenone (3.0 g, 14.0 mmol), 1 equiv of TiCl4 (1.54 ml, 14.0 mmol), and 2 equiv of Zn dust (1.83 g, 28.0 mmol) in 100 ml of dry THF was refluxed for 20 h. The reaction mixture was cooled to room temperature and filtered. The filtrates were evaporated and the crude product was purified by a silica gel column using ethyl acetate (EA) as eluent. DHTPE was obtained as slight yellow powder of 83% yield.

Источник