Реакция #1164703

Уравнение реакции

5,6-diamino-1,3-diethyluracil

3-bromocinnamic acid

→

Compound 161

Выход 51.1%

(E)-8-(3-Bromostyryl)-1,3-diethylxanthine

Выход 51.1%

Условия реакции

Обработка

1. 1
   ДругоеThen, the resultant crude crystals were recrystallized from tetrahydrofuran/water

Методика

Substantially the same procedure as in Reference Example 70 was repeated using 2.0 g (10.1 mmol) of 5,6-diamino-1,3-diethyluracil and 2.52 g (11.1 mmol) of 3-bromocinnamic acid. Then, the resultant crude crystals were recrystallized from tetrahydrofuran/water to give 2.01 g (yield 37%) of Compound 161 as pale green plates.

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