Реакция #11634

Уравнение реакции

3-hydroxymethylene-6-(3-methoxy-phenyl)-1,3-dihydro-indol-2-one

4-morpholin-4-yl-phenylamine

→

compound

6-(3-Methoxy-phenyl)-3-{[4-morpholin-4-yl-phenylamino)-methylene]-1,3-dihydro-indol-2-one

Растворители

tetrahydrofuran

Условия реакции

Обработка

1. 1
   ДругоеThe named compound is prepared
2. 2
   Другоеsolvent evaporation in vacuo, trituration
3. 3
   Фильтрацияwith isopropanol and filtration the reaction

Методика

The named compound is prepared by refluxing 0.020 gms E & Z 3-hydroxymethylene-6-(3-methoxy-phenyl)-1,3-dihydro-indol-2-one with 0.020 gms. 4-morpholin-4-yl-phenylamine in tetrahydrofuran (0.33 mL) for 2 days. Following cooling to room temperature, solvent evaporation in vacuo, trituration with isopropanol and filtration the reaction yields the named compound as a solid in the amount of 15.7 mg.

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