Реакция #1135806

Уравнение реакции

1-methoxy-2-methyl-3-aminobenzene

triphosgene

→

1-methoxy-3-isocyanato-2-methylbenzene

Выход 95.3%

Растворители

toluene

Условия реакции

Обработка

1. 1
   Температураwith heating
2. 2
   Температураunder reflux for three hours
3. 3
   Температураto cool
4. 4
   Концентрированиеwere concentrated under reduced pressure

Методика

A mixture of 1-methoxy-2-methyl-3-aminobenzene 15.0 g, triphosgene 48.7 g and toluene 350 mL was stirred with heating under reflux for three hours. The reaction mixtures after standing to cool were concentrated under reduced pressure to give 1-methoxy-3-isocyanato-2-methylbenzene 17.0 g.

Источник