Реакция #1135798

Уравнение реакции

1-chloro-2-methyl-3-methoxycarbonylaminobenzene

phosphorus pentachloride

→

1-chloro-3-isocyanato-2-methylbenzene

Растворители

chlorobenzene

Условия реакции

Обработка

1. 1
   Температураwith heating
2. 2
   Температураunder reflux for one hour
3. 3
   ДругоеThe reaction mixtures
4. 4
   Концентрированиеwere concentrated under reduced pressure

Методика

A mixture of the above-mentioned 1-chloro-2-methyl-3-methoxycarbonylaminobenzene 5.80 g, phosphorus pentachloride 7.53 g and chlorobenzene 50 mL was stirred with heating under reflux for one hour. The reaction mixtures were concentrated under reduced pressure to give 1-chloro-3-isocyanato-2-methylbenzene.

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