Реакция #11347

Уравнение реакции

Thionyl chloride

benzothiazole-6-sulfonic acid

dimethylformamide

→

6-Chlorosulfonylbenzothiazole

Растворители

dichloroethane

Условия реакции

Обработка

1. 1
   Температураthe reaction mixture was heated
2. 2
   Температураat reflux
3. 3
   Другоеto yield a clear solution
4. 4
   Температураat reflux
5. 5
   Другоеthe solvent was removed in vacuo and excess HCl and thionyl chloride
6. 6
   Другоеwas chased by evaporation with dichloroethane

Методика

Thionyl chloride (4 mL) was added to a suspension of the benzothiazole-6-sulfonic acid (0.60 g, 2.79 mmol) in dichloroethane (15 mL) and the reaction mixture was heated at reflux and dimethylformamide (5 mL) was added to the reaction mixture to yield a clear solution. After 1.5 hr. at reflux, the solvent was removed in vacuo and excess HCl and thionyl chloride was chased by evaporation with dichloroethane.

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