Реакция #1117

ord-604b730a698f47929475fa327db8b570

Уравнение реакции

CCc1nccc(Cl)c1Cl
3,4-dichloro-2-ethylpyridine
COCCOc1ccc(C2CCC(N)CC2)cc1
4-(4-(2-methoxyethoxy)phenyl)cyclohexylamine
→
CCc1nccc(NC2CCC(c3ccc(OCCOC)cc3)CC2)c1Cl
3-Chloro-4-[4-(4-(2-methoxyethoxy)phenyl)cyclohexylamino)-2-ethylpyridine
Выход 11.0%

Реактанты

CCc1nccc(Cl)c1Cl
3,4-dichloro-2-ethylpyridine
COCCOc1ccc(C2CCC(N)CC2)cc1
4-(4-(2-methoxyethoxy)phenyl)cyclohexylamine

Реагенты

Нет

Условия реакции

Подробные условия
See reaction.notes.procedure_details.

Обработка

  1. 1
    ДругоеPreparation

Методика

Preparation took place analogously to Example 59 from 3,4-dichloro-2-ethylpyridine and 4-(4-(2-methoxyethoxy)phenyl)cyclohexylamine. Yield: 11% (cis/trans mixture)

Источник

DOI: 10.6084/m9.figshare.5104873.v1Патент: US05723450uspto-grants-1998_03