Реакция #1106682

Уравнение реакции

C-Benzo[1,3]dioxol-2-yl-methylamine

sulfamide

→

title compound

(Benzo[1,3]dioxol-2-ylmethyl)sulfamide

Растворители

dioxane

Условия реакции

Обработка

1. 1
   Температураthe solution was heated
2. 2
   Температураto reflux overnight
3. 3
   КонцентрированиеThe reaction was concentrated
4. 4
   Другоеthe residue was chromatographed (2% to 10% acetone in dichloromethane)

Методика

C-Benzo[1,3]dioxol-2-yl-methylamine (2.94 g, 19.4 mmol) and sulfamide (3.74 g, 38.9 mmol) were combined in dry dioxane (50 mL) and the solution was heated to reflux overnight. The reaction was concentrated and the residue was chromatographed (2% to 10% acetone in dichloromethane) to yield the title compound as a white solid.

Источник