Реакция #10912

Уравнение реакции

cyanamide

1-(4-isothiocyanatophenyl)-4-cyclopropylmethylpiperazine

1-(4-Isothiocyanatophenyl)-4-(1-cyclopropylmethyl)piperazine

2-bromo-1-(3-methoxyphenyl)ethanone

→

{4-Amino-2-[4-(4-cyclopropylmethyl-piperazin-1-yl)-phenylamino]-thiazol-5-yl}-(3-methoxy-phenyl)-methanone

Условия реакции

Методика

This compound was prepared from cyanamide, 1-(4-isothiocyanatophenyl)-4-cyclopropylmethylpiperazine (of Example 14G) and 2-bromo-1-(3-methoxyphenyl)ethanone (Aldrich) following the procedure used in Example 24 Mass spectrum (ES) MH+=464.

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