Реакция #1010883

Уравнение реакции

carbazole

1-bromo-2-iodobenzene

potassium carbonate

→

9-(2-bromophenyl)-9H-carbazole

Растворители

xylene

Условия реакции

Обработка

1. 1
   Экстракцияextracted with ethyl acetate
2. 2
   Сушкаdried with anhydrous magnesium sulfate
3. 3
   Другоеto remove moisture
4. 4
   Другоеthe solvent was removed under reduced pressure
5. 5
   ДругоеSilica gel column separation
6. 6
   Другоеthus obtaining a compound from which the solvent
7. 7
   Другоеwas then removed under reduced pressure
8. 8
   Другоеdrying

Методика

1.672 g of carbazole, 1.6 mL of 1-bromo-2-iodobenzene, 2.7646 g of potassium carbonate, 95 mg of copper iodide and 25 mL of xylene were refluxed in a nitrogen atmosphere. The mixture was cooled to room temperature, extracted with ethyl acetate, and dried with anhydrous magnesium sulfate to remove moisture, and the solvent was removed under reduced pressure. Silica gel column separation using a hexane solvent was conducted, thus obtaining a compound from which the solvent was then removed under reduced pressure, followed by vacuum drying, yielding 9-(2-bromophenyl)-9H-carbazole as a desired white solid intermediate.

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