Dioxane

CC(C)(C)OC(=O)Nc1cc(F)ccn1
Reaction #109
Выход 19.5%750 AstraZeneca ELN dataset
COc1cc(C=O)ccc1Nc1ncc(Cl)c(-c2cnc3ccccn23)n1
Reaction #110
Выход 34.9%750 AstraZeneca ELN dataset
CN1CCc2cccc(Nc3cc(Cl)ncc3Cl)c2C1=O
Reaction #118
Выход 42.5%750 AstraZeneca ELN dataset
CN1CCc2cccc(Nc3cc(Cl)ncc3Cl)c2C1=O
Reaction #119
Выход 63.3%750 AstraZeneca ELN dataset
CN1CCc2cccc(Nc3cc(Cl)ncc3Cl)c2C1=O
Reaction #120
Выход 49.4%750 AstraZeneca ELN dataset
CN1CCc2cccc(Nc3cc(Cl)ncc3Cl)c2C1=O
Reaction #121
Выход 59.5%750 AstraZeneca ELN dataset
CONC(=O)c1ccccc1Nc1cc(Cl)ncc1Cl
Reaction #122
Выход 39.1%750 AstraZeneca ELN dataset
CONC(=O)c1ccccc1Nc1cc(Cl)ncc1Cl
Reaction #123
Выход 69.2%750 AstraZeneca ELN dataset
CNC(=O)c1ccccc1Nc1cc(Cl)ncc1Cl
Reaction #124
Выход 69.4%750 AstraZeneca ELN dataset
CNC(=O)c1ccccc1Nc1cc(Cl)ncc1Cl
Reaction #125
Выход 32.1%750 AstraZeneca ELN dataset
Cc1ncc(-c2nc(Nc3ccc(CN4CCOCC4)cc3F)ncc2F)n1C1CCOCC1
Reaction #126
Выход 9.1%750 AstraZeneca ELN dataset
Cc1ncc(-c2nc(Nc3ccc(CN4CCOCC4)cc3F)ncc2F)n1C1CCOCC1
Reaction #127
Выход 11.4%750 AstraZeneca ELN dataset
Cc1cnc(Nc2nc(N[C@@H](C)c3ncc(F)cn3)nc(N3CCOCC3)n2)s1
Reaction #128
Выход 20.7%750 AstraZeneca ELN dataset
CNC(=O)c1ccccc1Nc1cc(Nc2cn(C)nc2C)ncc1C#N
Reaction #129
Выход 50.0%750 AstraZeneca ELN dataset
CNC(=O)c1ccccc1Nc1cc(Nc2cc(OC)nn2C)ncc1C#N
Reaction #130
Выход 54.7%750 AstraZeneca ELN dataset
Cc1nn(C)cc1Nc1cc(Nc2cccc3c2C(=O)N(C)CC3)c(C#N)cn1
Reaction #131
Выход 7.3%750 AstraZeneca ELN dataset
O=C(Nc1cc(Nc2c(Cl)cnc3c2OCO3)ccn1)C1CC1
Reaction #136
Выход 32.2%750 AstraZeneca ELN dataset
O=C(Nc1cc(Nc2c(Cl)cnc3c2OCO3)ccn1)C1CC1
Reaction #137
Выход 28.4%750 AstraZeneca ELN dataset
O=C(Nc1cc(Nc2c(Cl)cnc3c2OCO3)ccn1)C1CC1
Reaction #138
Выход 70.9%750 AstraZeneca ELN dataset
O=C(Nc1cc(Nc2c(Cl)cnc3c2OCO3)ccn1)C1CC1
Reaction #139
Выход 43.7%750 AstraZeneca ELN dataset
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