#2743

CCOC(=O)c1cnc2cc(OCC)c(N3CCN(C(C)C)CC3)cc2c1Nc1ccc(F)cc1F
Reaction #97
Выход 65.4%750 AstraZeneca ELN dataset
COC(=O)c1cc2c(ncn2C)c(F)c1Nc1ccccc1
Reaction #98
Выход 57.5%750 AstraZeneca ELN dataset
COC(=O)c1cc2c(ncn2C)c(F)c1Nc1ccccc1
Reaction #99
Выход 65.4%750 AstraZeneca ELN dataset
COC(=O)c1cc2c(ncn2C)c(F)c1Nc1ccccc1
Reaction #100
Выход 75.1%750 AstraZeneca ELN dataset
CC(C)(C)OC(=O)Nc1cc(F)ccn1
Reaction #109
Выход 19.5%750 AstraZeneca ELN dataset
COc1cc(C=O)ccc1Nc1ncc(Cl)c(-c2cnc3ccccn23)n1
Reaction #110
Выход 34.9%750 AstraZeneca ELN dataset
Cc1ncc(-c2nc(Nc3ccc(CN4CCOCC4)cc3F)ncc2F)n1C1CCOCC1
Reaction #126
Выход 9.1%750 AstraZeneca ELN dataset
Cc1ncc(-c2nc(Nc3ccc(CN4CCOCC4)cc3F)ncc2F)n1C1CCOCC1
Reaction #127
Выход 11.4%750 AstraZeneca ELN dataset
Cc1cnc(Nc2nc(N[C@@H](C)c3ncc(F)cn3)nc(N3CCOCC3)n2)s1
Reaction #128
Выход 20.7%750 AstraZeneca ELN dataset
CCN1CCN(c2ccc(-c3cccc4c(=O)cc(N5CCOCC5)oc34)c3sc4ccccc4c23)CC1
Reaction #141
Выход 0.0%750 AstraZeneca ELN dataset
CONC(=O)c1ccccc1Nc1cc(Nc2cn(C)nc2C)ncc1Cl
Reaction #146
Выход 14.3%750 AstraZeneca ELN dataset
Cc1ncc(-c2nc(Nc3ccc(CN4CCOCC4)cc3)ncc2F)n1C1CCOCC1
Reaction #149
Выход 85.5%750 AstraZeneca ELN dataset
Cc1ncc(-c2nc(Nc3ccc(CN4CCOCC4)cc3)ncc2F)n1C1CCOCC1
Reaction #150
Выход 53.7%750 AstraZeneca ELN dataset
Cc1ncc(-c2nc(Nc3ccc(CN4CCOCC4)cc3)ncc2F)n1C1CCOCC1
Reaction #151
Выход 6.3%750 AstraZeneca ELN dataset
Cc1ncc(-c2nc(Nc3ccc(CN4CCOCC4)cc3)ncc2F)n1C1CCOCC1
Reaction #152
Выход 0.0%750 AstraZeneca ELN dataset
Cc1ncc(-c2nc(Nc3ccc(CN4CCOCC4)cc3)ncc2F)n1C1CCOCC1
Reaction #153
Выход 33.8%750 AstraZeneca ELN dataset
Cc1ncc(-c2nc(Nc3ccc(CN4CCOCC4)cc3)ncc2F)n1C1CCOCC1
Reaction #154
Выход 79.3%750 AstraZeneca ELN dataset
COc1cccc2sc(Nc3ccccc3)nc12
Reaction #158
Выход 15.2%750 AstraZeneca ELN dataset
N#Cc1ccc(Nc2ccc(C(=O)NC3CCCCC3)cn2)cc1
Reaction #169
Выход 9.9%750 AstraZeneca ELN dataset
Clc1nccc(N2CCCc3ccccc32)n1
Reaction #171
Выход 7.3%750 AstraZeneca ELN dataset
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