반응 #985262

반응 방정식

2-(4-nitrophenyl)benzothiazole

tin (II) chloride dihydrate

→

2-(4-Aminophenyl)benzothiazole

용매

ethanol

반응 조건

후처리

1. 1
   온도was refluxed under N2 for 4 hrs
2. 2
   기타After removing ethanol
3. 3
   기타by vacuum evaporation
4. 4
   workup.DISSOLUTIONThe residue was dissolved into ethyl acetate (20 ml)
5. 5
   세척washed with NaOH solution (1 N, 3×20 ml) and water (3×20 ml)
6. 6
   기타dried
7. 7
   기타evaporated to dryness to givelo2 mg (97%) of the product

실험 절차

A mixture of 2-(4-nitrophenyl)benzothiazole (105 mg, 0.40 mmol) and tin (II) chloride dihydrate (205 mg, 0.91 mmol) in ethanol (20 mL) was refluxed under N2 for 4 hrs. After removing ethanol by vacuum evaporation. The residue was dissolved into ethyl acetate (20 ml), and washed with NaOH solution (1 N, 3×20 ml) and water (3×20 ml), dried and evaporated to dryness to givelo2 mg (97%) of the product

출처