반응 #9817

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7-Nitro-4H-benzo[1,4]thiazin-3-one

sodium hydride

methyl iodide

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title product

7-Nitro-4-methyl-4H-benzo[1,4]thiazin-3-one

용매

DMF

DMF

반응 조건

후처리

1. 1
   workup.ADDITIONwere added dropwise

실험 절차

7.3 g 7-Nitro-4H-benzo[1,4]thiazin-3-one was suspended in 65 ml DMF and treated in portions with 1.6 g of 55% sodium hydride. Stirring a room temperature was continued for 0.5 hrs, than 5.2 g methyl iodide in 15 ml DMF were added dropwise. After another 3 hrs the mixture was poured into ice water and the title product isolated by filtration in a yield of 7.5 g.

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