반응 #9815

반응 방정식

6-Nitro-2,3-dihydro-benzo[1,4]oxathiine-4,4-dioxide

hydrogen

→

title compound

수율 46.4%

6-Amino-2,3-dihydro-benzo[1,4]oxathiine-4,4-dioxide

수율 46.4%

용매

THF

MeOH

반응 조건

후처리

1. 1
   여과The catalyst was filtered off
2. 2
   기타the filtrate evaporated
3. 3
   기타the residue chromatographed on silica

실험 절차

0.917 g 6-Nitro-2,3-dihydro-benzo[1,4]oxathiine-4,4-dioxide (from g)) were hydrogenated in a mixture of 20 ml THF and 20 ml MeOH with 0.90 g 5% Pd—C at atmospheric hydrogen pressure for 90 min. at room temperature. The catalyst was filtered off, the filtrate evaporated and the residue chromatographed on silica to yield 370 mg of the title compound.

출처