반응 #9784

ord-b4b250cb2381419385197056ebaf170b

반응 방정식

COC(=O)c1cc(-c2ccc(C(F)(F)F)cc2)oc1CBr
methyl 2-(bromomethyl)-5-[4-(trifluoromethyl)phenyl]-3-furoate
COC(=O)c1cc(-c2ccc(C(F)(F)F)cc2)oc1CBr
Methyl 2-bromomethyl-5-[4-(trifluoromethyl)phenyl]-3-furoate
COC(=O)c1cc(-c2ccc(C(F)(F)F)cc2)oc1CBr
intermediate 44
COC(=O)c1cc(-c2ccc(C(F)(F)F)cc2)oc1CBr
Methyl 2-bromomethyl-5-[4-(trifluoromethyl)phenyl]-3-furoate
COc1ccc(N2CCNCC2)cc1
1-(4-methoxyphenyl)piperazine
COc1ccc(N2CCN(Cc3oc(-c4ccc(C(F)(F)F)cc4)cc3CO)CC2)cc1
title compound
COc1ccc(N2CCN(Cc3oc(-c4ccc(C(F)(F)F)cc4)cc3CO)CC2)cc1
{2-{[4-(4-methoxyphenyl)piperazin-1-yl]methyl}-5-[4-(trifluoromethyl)phenyl]-3-furyl}methanol

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

The title compound was prepared using methyl 2-(bromomethyl)-5-[4-(trifluoromethyl)phenyl]-3-furoate (intermediate 44) and 1-(4-methoxyphenyl)piperazine.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US07091237B2uspto-grants-2006_08