반응 #976979

반응 방정식

compound 2

4-Phenylacetyl-1H-pyrrole-2-carboxylic acid benzylamide

(Me2N)2CHOt-Bu

→

4-(3-Dimethylamino-2-phenyl-acryloyl)-1H-pyrrole-2-carboxylic acid benzylamide

용매

THF

반응 조건

후처리

1. 1
   기타the solvent was evaporated
2. 2
   기타the crude product 3 was utilized without purification

실험 절차

To a solution of compound 2 (1 equivalent) in THF, at ambient temperature, was added (Me2N)2CHOt-Bu (3 equivalents). After 24 hours, the solvent was evaporated and the crude product 3 was utilized without purification. 1H NMR (CDCl3) □ 4.4 (s, 2H), 4.8 (s, NH), 6.8–7.4 (m, 13H).

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