반응 #95944

반응 방정식

diethylenetriamine

methyl acetoacetate

lauric acid

→

4-lauramidoethyl-7-methyl-3,6-dihydro-2H-1,4-diazepin-5-one

반응 조건

후처리

1. 1
   workup.DISTILLATIONAt 140° to 150° C., 18 g of water and 32 g of methanol were distilled off
2. 2
   기타was effected at 200° to 210° C.
3. 3
   workup.DISTILLATION18 g of water was distilled off

실험 절차

Into an apparatus similar to that in Example 1, were charged 103.1 g (1 mole) of diethylenetriamine and 116.1 g (1 mole) of methyl acetoacetate. At 140° to 150° C., 18 g of water and 32 g of methanol were distilled off. Then, with the addition of 200.3 g (1 mole) of lauric acid, the amide formation was effected at 200° to 210° C. and 18 g of water was distilled off, leaving behind 4-lauramidoethyl-7-methyl-3,6-dihydro-2H-1,4-diazepin-5-one.

출처