반응 #9566

반응 방정식

7-bromo-4-chloro-3-nitroquinoline

C-(tetrahydropyran-4-yl)methylamine

→

(7-bromo-3-nitroquinolin-4-yl)(tetrahydropyran-4-ylmethyl)amine

수율 94.3%

반응 조건

실험 절차

The method described in Part E of Examples 431–436 was used to treat 7-bromo-4-chloro-3-nitroquinoline (12.43 g, 43.45 mmol) with C-(tetrahydropyran-4-yl)methylamine (10 g, 87 mmol) to provide 15.0 g of (7-bromo-3-nitroquinolin-4-yl)(tetrahydropyran-4-ylmethyl)amine as a bright yellow solid.

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