반응 #955971

반응 방정식

thiophene-3,4-dicarboxylic anhydride

4-(3-ethylheptyl)-2,3,5,6-tetrafluoroaniline

→

5-(4-(3-ethylheptyl)-2,3,5,6-tetrafluorophenyl)-4H-thieno[3,4-c]pyrrole-4,6(5H)-dione

용매

toluene

반응 조건

후처리

1. 1
   여과The crude product is collected by filtration of the cold reaction mixture
2. 2
   기타Another portion of product can be recovered
3. 3
   세척by washing the filtrate with 5% hydrochloric acid
4. 4
   기타evaporating the solvent
5. 5
   기타The target molecule is purified by recrystallization from toluene
6. 6
   workup.DISSOLUTIONdissolved in 150 ml of thionyl chloride
7. 7
   온도refluxed for 3 hrs
8. 8
   농축The reaction mixture is concentrated down
9. 9
   기타dried
10. 10
    기타purified

실험 절차

A solution of thiophene-3,4-dicarboxylic anhydride (8.0 mmol) and 4-(3-ethylheptyl)-2,3,5,6-tetrafluoroaniline (8.5 mmol) in 125 ml of toluene is refluxed for 24 h. The crude product is collected by filtration of the cold reaction mixture. Another portion of product can be recovered by washing the filtrate with 5% hydrochloric acid and then evaporating the solvent. The target molecule is purified by recrystallization from toluene, dissolved in 150 ml of thionyl chloride and refluxed for 3 hrs. The reaction mixture is concentrated down, dried, and purified.

출처